Mike Klymkowsky from University of Colorado-Boulder explains how the clamp and clamp loader work during transcription in this 2:36 minute YouTube video.
A mutation of repeated DNA causes transcription to start in the wrong location and creates a novel, toxic protein. A 2013 article from Science.Daily.com
Researcher James DeGregori claims aging tissue, rather than buildup of DNA mutations, is the reason cancer is more prevalent in the elderly. A 2012 article from ScienceDaily.com
A 2007 blog entry from Sandwalk: A Stroll with a Skeptical Biochemist, written by Laurence A. Moran, Professor of Biochemistry at the University of Toronto.
An entry from Kimball's Pages on point mutations and their harmful or beneficial impact on organisms. John Kimball is a retired biology professor who taught at Tufts University and Harvard.